Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082843 | 0.90 | DGAT1 (0.41) | SMN1; SMN2LMNADGAT1PTPRBHIF1A | |
| SCHEMBL27587968 | 0.90 | DGAT1 (0.41) | SMN1; SMN2LMNADGAT1PTPRBHIF1A | |
| SCHEMBL27850077 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKMT2ACTSSCTSK | |
| SCHEMBL16553913 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKMT2ACTSSCTSK | |
| SCHEMBL27867247 | 0.88 | BLM (0.50) | SMN1; SMN2KMT2ACTSSCTSKDGAT1 | |
| SCHEMBL8609662 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2RECQLDGAT1PTPRBHIF1A | |
| SCHEMBL8609659 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2RECQLDGAT1PTPRBHIF1A | |
| SCHEMBL28790671 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2KMT2ANPC1RAB9ADGAT1 | |
| SCHEMBL27726815 | 0.83 | CTSB (0.44) | LMNACTSSCTSKL3MBTL1KDM4E | |
| SCHEMBL27477063 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKMT2ARECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102378574-A | Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof | TRANSTECH PHARMA INC | 2012-03-14 | — | — | CN | disclosed |