Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075846 | 0.85 | CA2 (0.41) | CA2 | |
| SCHEMBL28193734 | 0.82 | CA2 (0.53) | CNR1CNR2CA2LPLLIPG | |
| SCHEMBL380954 | 0.81 | CNR1 (0.50) | CNR1CNR2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31319048 | 0.79 | KAT6A (0.50) | KAT6ACNR1CNR2CA2METAP2 | |
| SCHEMBL331257 | 0.79 | KAT6A (0.50) | KAT6ACNR1CNR2CA2METAP2 | |
| SCHEMBL28040551 | 0.78 | CA2 (0.34) | KAT6ACNR1CNR2CA2 | |
| SCHEMBL28032990 | 0.78 | KAT6A (0.49) | KAT6ACNR1CNR2CA2METAP2 | |
| Phenylmethanesulfonic Acid SCHEMBL1985262 | 0.78 | PRSS1 (0.50) | CA2 | |
| SCHEMBL28136847 | 0.76 | MAOA (0.47) | KAT6ACA2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3894959 | 0.76 | ALDH1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666620-A | Hydrophilically-modified silicone compositions | DOW CORNING | 2012-09-12 | — | — | CN | disclosed |