Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874932 | 1.00 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL28930085 | 1.00 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL6610765 | 1.00 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL6612881 | 1.00 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL7947857 | 1.00 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL26136867 | 1.00 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL8755575 | 0.98 | TSHR (0.52) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL15923516 | 0.91 | TSHR (0.56) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL20377446 | 0.91 | TSHR (0.56) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL9455617 | 0.91 | TSHR (0.56) | TSHRHTTTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727944-B2 | Lubricant compositions containing seal conditioning agents | THE LUBRIZOL CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070298984-A1 | Lubricant Compositions Containing Seal Conditioning Agents | THE LUBRIZOL CORPORATION (US) | 2007-12-27 | — | — | US | disclosed |
| EP-1841846-A1 | ENGINE FLUSH PROCESS AND COMPOSITION | The Lubrizol Corporation (an Ohio corporation) (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006060255-A1 | ENGINE FLUSH PROCESS AND COMPOSITION | THE LUBRIZOL CORPORATION (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20060116297-A1 | Engine flush process and composition | THE LUBRIZOL CORPORATION (US) | 2006-06-01 | — | — | US | disclosed |
| WO-2006023317-A1 | LUBRICANT COMPOSITIONS CONTAINING SEAL CONDITIONING AGENTS | THE LUBRIZOL CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |
| US-5981580-A | IN WHICH THE CARBOXY-TERMINUS HAS BEEN MODIFIED TO FORM VARIOUS AMIDES, ESTERS, KETONES, ALCOHOLS, ALCOHOL ESTERS AND NITRITES THEREOF, AND ARE USEFUL AS SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME | G. D. SEARLE & CO. (US) | 1999-11-09 | — | — | US | disclosed |
| US-5952377-A | SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME, AS ANTI-VIRAL AND ANTI-FUNGAL AGENTS OR PRO-DRUGS; TREATING AIDS, LENTIVIRUSES SUCH AS THE HUMAN IMMUNODEFICIENCY VIRUS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5929110-A | USEFUL AS SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME, AND AS ANTI-VIRAL AND ANTI-FUNGAL AGENTS OR PRO-DRUGS OF SUCH AGENTS | G. D. SEARLE & CO. (US) | 1999-07-27 | — | — | US | disclosed |
| US-5859052-A | TREATING LENTIVIRUS INFECTIONS, ESPECIALLY HUMAN IMMUNODEFICIENCY VIRUS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5744631-A | Fatty acid analogs and prodrugs | G.D. SEARLE & CO. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5719290-A | METHYLOXYUNDECYL- OR DECYLOXYETHYL-NITRILE OR TETRAZOLE DERIVATIVES; VIRICIDES | G. D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5672769-A | CHEMICAL INTERMEDIATES FOR VIRICIDES, FUNGICIDES | G. D. SEARLE & CO. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5670650-A | ANTIVIRAL AND ANTIFUNGAL AGENTS | G. D. SEARLE & CO. (US) | 1997-09-23 | — | — | US | disclosed |
| US-5599947-A | VIRICIDES, FUNGICIDES OR THEIR PRODRUGS | G. D. SEARLE & CO. (US) | 1997-02-04 | — | — | US | disclosed |
| US-4491525-A | Oil recovery with surfactant flooding | PHILLIPS PETROLEUM COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4335787-A | SURFACTANT SYSTEM COMPRISING A HYDROCARBON SULFONATE AND A NITRILE | PHILLIPS PETROLEUM COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298984-A1 | Lubricant Compositions Containing Seal Conditioning Agents | GPX4, ALOX5, ALOX15 | TSHR 4884/4885HTT 3243/4885THRB 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.