Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PRF1 | P14222 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.34 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150874 | 0.70 | ATM (0.40) | ALDH1A1ATMKMT2AGLAMEN1 | |
| SCHEMBL2045397 | 0.67 | ALDH1A1 (0.42) | ALDH1A1KMT2AGLAIDO1TDO2 | |
| SCHEMBL8022126 | 0.66 | HPGD (0.42) | ALDH1A1ATMKMT2AMEN1MAPT | |
| SCHEMBL21061394 | 0.66 | ALDH1A1 (0.37) | ALDH1A1ATMKMT2AGLAIDO1 | |
| SCHEMBL1521514 | 0.66 | MAPT (0.47) | ALDH1A1ATMPRF1MAPTGAA | |
| SCHEMBL21674388 | 0.65 | MAOA (0.40) | ALDH1A1ATMKMT2AGLAMEN1 | |
| SCHEMBL1944062 | 0.64 | MAPT (0.46) | ALDH1A1ATMPRF1MAPTGAA | |
| SCHEMBL3010030 | 0.64 | MAPT (0.46) | ALDH1A1ATMPRF1MAPTGAA | |
| SCHEMBL450892 | 0.64 | MAPT (0.39) | ALDH1A1KMT2AGLAIDO1TDO2 | |
| SCHEMBL13269472 | 0.64 | ALDH1A1 (0.41) | ALDH1A1KMT2AGLAIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540309-B2 | Methylidene malonate process | OPTMED, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9487468-B2 | Methylidene malonate process | OPTMED, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20150203437-A1 | METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2015-07-23 | — | — | US | disclosed |
| US-20150183714-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2015-07-02 | — | — | US | disclosed |
| US-8993795-B2 | Methylidene malonate process | OPTMED INC (US) | 2015-03-31 | — | — | US | disclosed |
| US-8975435-B2 | Methylidene malonate process | OPTMED, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20130012736-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2013-01-10 | — | — | US | disclosed |
| US-20130008773-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2427423-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | Optmed Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| EP-2427422-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | Optmed Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-8106234-B2 | Methylidene malonate process | OptMed, Inc (US) | 2012-01-31 | — | — | US | disclosed |
| US-20100286439-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. | 2010-11-11 | — | — | US | disclosed |
| US-20100286438-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. | 2010-11-11 | — | — | US | disclosed |
| US-20100286433-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. | 2010-11-11 | — | — | US | disclosed |
| WO-2010129066-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010129068-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010129067-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012736-A1 | METHYLIDENE MALONATE PROCESS | MPHOSPH6, ME1, MGAM | ALDH1A1 1618/4885ATM 743/4885KMT2A 972/4885 |
| US-20100286439-A1 | METHYLIDENE MALONATE PROCESS | MPHOSPH6, ME1, MGAM | ALDH1A1 1618/4885ATM 743/4885KMT2A 972/4885 |
| US-20100286438-A1 | METHYLIDENE MALONATE PROCESS | MPHOSPH6, ME1, MGAM | ALDH1A1 1618/4885ATM 743/4885KMT2A 972/4885 |
| US-20100286433-A1 | METHYLIDENE MALONATE PROCESS | MMAB, ME1, MAL2 | ALDH1A1 1265/4885ATM 262/4885KMT2A 384/4885 |
| US-20150183714-A1 | METHYLIDENE MALONATE PROCESS | MPHOSPH6, ME1, MGAM | ALDH1A1 1618/4885ATM 743/4885KMT2A 972/4885 |
| US-20150203437-A1 | METHYLIDENE MALONATE PROCESS | MMAB, ME1, MAL2 | ALDH1A1 1265/4885ATM 262/4885KMT2A 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.