SCHEMBL2879752

SCHEMBL2879752

Clc1ccc(P(Cl)Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
CYP2A6 P11509 1/20 0.53
IDO1 P14902 2/20 0.41
TSHR P16473 5/20 0.37
CYP1A2 P05177 1/20 0.36
SLC6A4 P31645 1/20 0.36
MAPK1 P28482 4/20 0.35
CYP3A4 P08684 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ENPP2 Q13822 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GSK3B P49841 2/20 0.35
HIF1A Q16665 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALOX15 P16050 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA1 P00915 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596456 1.00 LMNA (0.53) LMNACYP2A6IDO1TSHRCYP1A2
SCHEMBL6032229 0.86
SCHEMBL6545142 0.84 MAOA (0.54) LMNACYP2A6CYP1A2ALDH1A1CA2
SCHEMBL2154365 0.80 LMNA (0.53) LMNACYP2A6IDO1TSHRCYP1A2
SCHEMBL152775 0.76 LMNA (0.57) LMNACYP2A6IDO1TSHRCYP1A2
Bromide SCHEMBL28414241 0.73 LMNA (0.53) LMNACYP2A6IDO1TSHRCYP1A2
SCHEMBL31325559 0.73 LMNA (0.53) LMNACYP2A6IDO1TSHRCYP1A2
SCHEMBL11551608 0.73 LMNA (0.53) LMNACYP2A6IDO1TSHRCYP1A2
1,4-Dichlorobenzene SCHEMBL11243685 0.73
1,4-Dichlorobenzene SCHEMBL5191 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798607-A Preparation method and application of photo-curing resin 万华化学集团股份有限公司 2025-04-11 CN claimed
CN-118496702-A High-flash-point fireproof coating based on heat-resistant phenyl phosphine oxide and preparation method thereof 江苏冠军科技集团股份有限公司 2024-08-16 CN claimed
CN-116589902-B High-flash-point modified epoxy fireproof paint and preparation method thereof 江苏冠军科技集团股份有限公司 2023-11-03 CN claimed
CN-116589902-A High-flash-point modified epoxy fireproof paint and preparation method thereof 江苏冠军科技集团股份有限公司 2023-08-15 CN claimed
CN-116120363-A Heat-resistant phenylphosphine oxide, modified cage type silsesquioxane, modified epoxy fireproof coating based on heat-resistant phenylphosphine oxide and modified cage type silsesquioxane, and preparation method of modified epoxy fireproof coating 江苏冠军科技集团股份有限公司 2023-05-16 CN claimed
EP-1354886-B1 Process for the preparation of tertiary phosphines SALTIGO GMBH (DE) 2009-08-26 EP claimed
US-7230136-B2 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2007-06-12 US claimed
US-20030229240-A1 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2003-12-11 US claimed
EP-1354886-A1 Process for the preparation of tertiary phosphines Bayer Aktiengesellschaft (DE) 2003-10-22 EP claimed
CN-119798607-B Preparation method and application of photo-curing resin 万华化学集团股份有限公司 2026-05-19 CN disclosed
CN-119798607-A Preparation method and application of photo-curing resin 万华化学集团股份有限公司 2025-04-11 CN disclosed
CN-118496702-A High-flash-point fireproof coating based on heat-resistant phenyl phosphine oxide and preparation method thereof 江苏冠军科技集团股份有限公司 2024-08-16 CN disclosed
CN-116589902-B High-flash-point modified epoxy fireproof paint and preparation method thereof 江苏冠军科技集团股份有限公司 2023-11-03 CN disclosed
CN-116589902-A High-flash-point modified epoxy fireproof paint and preparation method thereof 江苏冠军科技集团股份有限公司 2023-08-15 CN disclosed
EP-0080149-B1 PROCESS FOR THE PREPARATION OF PHOSPHOROUS ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-09 EP disclosed
EP-0126501-A2 Process for the preparation of alpha-haloalkyl esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-11-28 EP disclosed
EP-0122587-A2 Process for preparing organic chlorophosphanes HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-24 EP disclosed
US-4138433-A Process for preparing 1,2-oxa-phospholanes HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4096182-A Process for the simultaneous preparation of 2,5-dioxo-1,2-oxa-phospholanes and β-halogenpropionic acid halide HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed
US-4000239-A PROCESS FOR SPINNING NAPHTHALATE POLYESTER FIBERS TEIJIN LIMITED (JA) 1976-12-28 US disclosed