Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154438 | 0.89 | TSHR (0.50) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL7596456 | 0.80 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL2879752 | 0.80 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL152775 | 0.76 | LMNA (0.57) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Bromide SCHEMBL28414241 | 0.73 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL31325559 | 0.73 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL11551608 | 0.73 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.73 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.73 | — | — | |
| SCHEMBL2153439 | 0.71 | TYR (0.41) | LMNAIDO1MAPK1HIF1ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530277-A | Cationic photopolymerization type phosphate alicyclic epoxy monomer and preparation method and application thereof | 北京化工大学 | 2024-08-23 | — | — | CN | claimed |
| CN-118530277-A | Cationic photopolymerization type phosphate alicyclic epoxy monomer and preparation method and application thereof | 北京化工大学 | 2024-08-23 | — | — | CN | disclosed |
| EP-3184171-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-12-04 | — | — | US | disclosed |
| US-9962689-B2 | Phosphinyl formamidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-10-26 | — | — | US | disclosed |
| US-9732106-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-08-15 | — | — | US | disclosed |
| EP-3184171-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | Chevron Phillips Chemical Company LP (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2519532-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20160375431-A1 | Phosphinyl Formamidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2016-12-29 | — | — | US | disclosed |
| US-6084133-A | REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY | KANKYO KAGAKU CENTER CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0683786-B1 | PROCESS FOR THE PREPARATION OF LITHIUM DIARYLPHOSPHIDES AND ALKYLATED DERIVATIVES THEREOF | EASTMAN CHEM CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5523453-A | USING NICKEL COMPLEX CATALYST AND LEWIS ACID PROMOTER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| US-5354894-A | Treating triarylphosphine with lithium and a primary or secondary amine | EASTMAN CHEMICAL COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5288912-A | Hydrohalogenation of a triarylphosphine; alkylation; using lithium diarylphosphine as chemical intermediate | EASTMAN KODAK COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0340985-B1 | PROCESS FOR PREPARING TRANS-2,2-DIMETHYL-3-(2,2-DIHALOVINYL)-CYCLOPROPANE CARBOXYLIC ACID HALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5008417-A | Haloalkylation process | ETHYL CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-4954651-A | Process for preparing trans-2,2-dimethyl-3-(2,2-dihalovinyl)-cyclopropane carboxylic acid halide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0340985-A1 | Process for preparing trans-2,2-dimethyl-3-(2,2-dihalovinyl)-cyclopropane carboxylic acid halide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-08 | — | — | EP | disclosed |
| US-RE29523-E | Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds | BORG-WARNER CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | NIT2, NCLN, NPM1 | LMNA 2832/4885CYP2A6 4835/4885IDO1 2456/4885 |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | LMNA 2832/4885CYP2A6 4835/4885IDO1 2456/4885 |
| US-20160375431-A1 | Phosphinyl Formamidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, INF2, PFAS | LMNA 3568/4885CYP2A6 4721/4885IDO1 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.