Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925043 | 0.92 | RORC (0.52) | RORCPOLQGRIK1MRGPRX4PPARG | |
| SCHEMBL29654248 | 0.89 | RORC (0.46) | RORCPOLQP2RX3PTGESSMN1; SMN2 | |
| SCHEMBL28797790 | 0.89 | RORC (0.46) | RORCPOLQP2RX3PTGESSMN1; SMN2 | |
| SCHEMBL28285110 | 0.84 | RORC (0.55) | RORCPOLQMRGPRX4PPARGGLP1R | |
| SCHEMBL21929295 | 0.82 | RORC (0.53) | RORCPOLQGRIK1PPARGGLP1R | |
| SCHEMBL20635537 | 0.81 | RORC (0.53) | RORCPOLQMRGPRX4PPARGMAPT | |
| SCHEMBL28797801 | 0.80 | RORC (0.70) | RORC | |
| SCHEMBL28797807 | 0.78 | RORC (0.72) | RORC | |
| SCHEMBL28797831 | 0.77 | RORC (0.57) | RORCPOLQMRGPRX4PPARG | |
| SCHEMBL29654191 | 0.77 | RORC (0.57) | RORCPOLQMRGPRX4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485595-B | Hydrophilic group substituted indole formamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |