Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887861 | 0.86 | POLB (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27514419 | 0.86 | KMT2A (0.51) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL27887849 | 0.86 | KDM4E (0.48) | ALDH1A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL27887879 | 0.79 | DPP4 (0.46) | KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9449932 | 0.72 | ALDH1A1 (0.55) | KMT2AALDH1A1MAPTHTR1AMAOA | |
| SCHEMBL11489056 | 0.72 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPTSLC6A2SLC6A4 | |
| SCHEMBL14775341 | 0.72 | SLC6A2 (0.74) | KMT2AALDH1A1MAPTHTR1AMAOA | |
| SCHEMBL29725293 | 0.71 | POLB (0.51) | KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3129710 | 0.71 | MMP2 (0.48) | KMT2AALDH1A1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL29135760 | 0.71 | GABBR2 (0.51) | KMT2AMAPTSMN1; SMN2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627587-A | Method for preparing 1-substituted tramiprosate from alpha, beta-unsaturated nitrile | UNIV BEIJING CHEMICAL | 2012-08-08 | — | — | CN | disclosed |