Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485820 | 0.84 | SLC7A5 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1396066 | 0.81 | ALDH1A1 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL60923 | 0.81 | TSHR (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6930076 | 0.81 | TSHR (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14485531 | 0.80 | DPP4 (0.37) | — | |
| Hydrochloric Acid SCHEMBL31223210 | 0.79 | TSHR (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3498360 | 0.79 | NAAA (0.32) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31283466 | 0.79 | GSR (0.52) | — | |
| SCHEMBL6019778 | 0.79 | RNPEP (0.37) | — | |
| SCHEMBL5874859 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762735-A | Microorganisms producing 1, 4-butanediol, 4-hydroxybutyraldehyde, 4-hydroxybutyryl-COA, putrescine and related compounds and related methods | GENOMATICA INC | 2012-10-31 | — | — | CN | disclosed |
| CN-102498215-A | Microorganisms for producing 1, 4-butanediol and related methods | GENOMATICA INC | 2012-06-13 | — | — | CN | disclosed |