Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883394 | 0.83 | TSHR (0.40) | POLBTSHRALDH1A1PPARGPPARA | |
| SCHEMBL10407604 | 0.71 | ATM (0.39) | POLBTSHRALDH1A1LIPE | |
| SCHEMBL21518490 | 0.70 | PPARG (0.44) | POLBTSHRALDH1A1PPARGPPARA | |
| SCHEMBL19975346 | 0.69 | MMP1 (0.48) | NR4A2ALDH1A1MEN1KMT2A | |
| SCHEMBL28766234 | 0.68 | PSMB11 (0.41) | POLBTSHRALDH1A1 | |
| SCHEMBL27872649 | 0.68 | PSMB11 (0.41) | POLBTSHRALDH1A1 | |
| SCHEMBL7377698 | 0.68 | CYP1A2 (0.47) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL4953717 | 0.68 | POLB (0.44) | POLBTSHRALDH1A1GAAPPARG | |
| SCHEMBL4953723 | 0.68 | POLB (0.44) | POLBTSHRALDH1A1GAAPPARG | |
| SCHEMBL28679009 | 0.68 | POLB (0.44) | POLBTSHRALDH1A1GAALIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102807600-A | Amino acid modified spinacin derivative and preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-12-05 | — | — | CN | disclosed |