Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800180 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAPDE2AMAPTL3MBTL1 | |
| SCHEMBL28800167 | 0.91 | ALDH1A1 (0.49) | ALDH1A1LMNAPDE2AMAPTL3MBTL1 | |
| SCHEMBL28800169 | 0.91 | ALDH1A1 (0.49) | ALDH1A1LMNAPDE2AMAPTL3MBTL1 | |
| SCHEMBL28800141 | 0.91 | TDP1 (0.47) | ALDH1A1LMNAPDE2AMAPTPKM | |
| SCHEMBL28800139 | 0.91 | TDP1 (0.47) | ALDH1A1LMNAPDE2AMAPTPKM | |
| SCHEMBL28800189 | 0.85 | PDE2A (0.48) | PDE2AL3MBTL1POLBPTGER4MAPK1 | |
| SCHEMBL28800187 | 0.85 | PDE2A (0.48) | PDE2AL3MBTL1POLBPTGER4MAPK1 | |
| SCHEMBL28800183 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAPDE2AMAPTL3MBTL1 | |
| SCHEMBL28800155 | 0.80 | TDP1 (0.49) | ALDH1A1PTGER4MAPK1 | |
| SCHEMBL28800158 | 0.80 | TDP1 (0.49) | ALDH1A1PTGER4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |