Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733257 | 0.78 | CYP3A4 (0.41) | KDM4EPARP1ALDH1A1MAPTHPGD | |
| SCHEMBL6233129 | 0.77 | CYP1A2 (0.41) | KDM4EBMPR1BPDGFRBKDRACVR1B | |
| SCHEMBL4177876 | 0.74 | TDP1 (0.41) | KDM4EBMPR1BPDGFRBKDRACVR1B | |
| SCHEMBL29733076 | 0.73 | MEN1 (0.50) | KDM4EACHECHRNB2CHRNA4MEN1 | |
| SCHEMBL6233506 | 0.73 | BMPR1B (0.36) | KDM4EBMPR1BPDGFRBKDRACVR1B | |
| Hydrochloric Acid SCHEMBL29733079 | 0.72 | MEN1 (0.49) | KDM4EACHECHRNB2CHRNA4MEN1 | |
| Hydrochloric Acid SCHEMBL29733077 | 0.72 | MEN1 (0.49) | KDM4EACHECHRNB2CHRNA4MEN1 | |
| Hydrochloric Acid SCHEMBL29733086 | 0.72 | MEN1 (0.49) | KDM4EACHECHRNB2CHRNA4MEN1 | |
| SCHEMBL5675376 | 0.70 | MEN1 (0.57) | ROCK2ROCK1ALDH1A1HPGDMEN1 | |
| SCHEMBL5675201 | 0.70 | MPO (0.44) | KDM4EPARP1ALDH1A1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102822172-A | Substituted naphthyridines and their use as syk kinase inhibitors | BOEHRINGER INGELHEIM INT | 2012-12-12 | — | — | CN | disclosed |