Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526057 | 0.80 | PRKCZ (0.38) | MEN1KMT2ASMN1; SMN2CYP1A2HTR2C | |
| SCHEMBL6233129 | 0.79 | CYP1A2 (0.41) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27608178 | 0.79 | BACE1 (0.41) | KMT2AHTR2CSLC6A4PARP1BACE1 | |
| SCHEMBL27627374 | 0.79 | BACE1 (0.41) | HTR2CHTTPARP1NCF1BACE1 | |
| SCHEMBL28752901 | 0.79 | HRH3 (0.37) | NPC1RAB9AKMT2AHIF1AKDM4E | |
| SCHEMBL16429508 | 0.79 | TAAR1 (0.49) | CYP3A4ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL28800404 | 0.78 | KDM4E (0.39) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9317927 | 0.78 | BACE1 (0.43) | PARP1BACE1 | |
| SCHEMBL8918069 | 0.77 | CYP2D6 (0.52) | CYP3A4ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6233506 | 0.75 | BMPR1B (0.36) | CYP3A4ALDH1A1MAPK1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120641-A | Incubating with sample, determining radioactivity | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0435192-A2 | Method for measurement of serotonin uptake sites and radioligand therefor | DAIICHI PURE CHEMICALS CO. LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |