SCHEMBL28800428

SCHEMBL28800428

CCCCC1=CC=C[C]1[Si](C)(CC)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27886295 0.91 KDM4E (0.31)
SCHEMBL28040367 0.85 HSD11B1 (0.35) HSD11B1POLB
SCHEMBL28040355 0.85 ESR1 (0.33) HSD11B1POLB
SCHEMBL27870072 0.84
SCHEMBL27953398 0.84 HSD11B1 (0.31) HSD11B1POLB
SCHEMBL27870084 0.83 HSD11B1 (0.33) HSD11B1POLB
SCHEMBL27870047 0.76
SCHEMBL28040849 0.75 ESR1 (0.35)
SCHEMBL28040369 0.75 KDM4E (0.33)
SCHEMBL27953349 0.74 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666561-B Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-11-25 CN disclosed
CN-102666607-B Olefinic polymers SUMITOMO CHEMICAL CO 2014-03-26 CN disclosed
CN-102666561-A Transition metal complex, preparation method for said transition metal complex, trimerization catalyst, preparation method for 1-hexene, preparation method for ethylene polymer, substituted cyclopentadiene compound, and preparation method for said su SUMITOMO CHEMICAL CO 2012-09-12 CN disclosed
CN-102666607-A Olefinic polymers SUMITOMO CHEMICAL CO 2012-09-12 CN disclosed