Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040849 | 0.90 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL28040367 | 0.88 | HSD11B1 (0.35) | HSD11B1POLBPARP1TLR8TLR7 | |
| SCHEMBL27870084 | 0.86 | HSD11B1 (0.33) | HSD11B1POLBPARP1CNR1 | |
| SCHEMBL28800428 | 0.85 | HSD11B1 (0.31) | HSD11B1POLB | |
| SCHEMBL27953398 | 0.83 | HSD11B1 (0.31) | ESR1HSD11B1POLBPARP1 | |
| SCHEMBL27886312 | 0.78 | CNR1 (0.31) | TLR7CNR1 | |
| SCHEMBL28040369 | 0.78 | KDM4E (0.33) | — | |
| SCHEMBL27887356 | 0.77 | PTGS2 (0.38) | ESR1 | |
| SCHEMBL27886271 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL27886295 | 0.75 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |