Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890835 | 0.80 | NR4A1 (0.44) | PSMD14KDM4ELMNATSHRALDH1A1 | |
| SCHEMBL27890846 | 0.79 | RPS6KB1 (0.44) | KDM4EGAAALDH1A1 | |
| SCHEMBL827213 | 0.78 | KDM4E (0.59) | KMT2AMEN1PSMD14KDM4EHSD17B10 | |
| SCHEMBL28319469 | 0.77 | KDM4E (0.48) | KMT2AMEN1PSMD14KDM4EGAA | |
| SCHEMBL27350076 | 0.76 | EGFR (0.38) | ATMLMNAALDH1A1HTTCYP1A2 | |
| SCHEMBL21187327 | 0.76 | L3MBTL1 (0.44) | CSNK2A1KDM4ETSHRHSD17B10HTT | |
| SCHEMBL21957454 | 0.76 | ALDH1A1 (0.46) | KMT2AMEN1PSMD14KDM4EGAA | |
| SCHEMBL21957370 | 0.76 | PLA2G2A (0.46) | KMT2AMEN1PSMD14KDM4EGAA | |
| SCHEMBL17798584 | 0.76 | TSHR (0.54) | KMT2AMEN1PSMD14KDM4EGAA | |
| SCHEMBL30052832 | 0.76 | PIM1 (0.51) | PSMD14KDM4EGAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102898417-A | Benzo-hexahydric nitrogenous heterocycle derivative | KBP BIOSCIENCES CO LTD | 2013-01-30 | — | — | CN | disclosed |