Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380801 | 0.84 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL3129277 | 0.80 | TDP1 (0.56) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL1220707 | 0.77 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL18304583 | 0.77 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AHTT | |
| SCHEMBL337736 | 0.76 | TDP1 (0.70) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL6869343 | 0.76 | TDP1 (0.59) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| Acetone SCHEMBL16013121 | 0.75 | TDP1 (0.63) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL10578604 | 0.75 | HDAC1 (0.56) | TDP1ALDH1A1KMT2AL3MBTL1NPC1 | |
| SCHEMBL27282391 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL8772358 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796618-A | Dental material for producing temporary crowns and bridges | 义获嘉伟瓦登特公司 | 2022-07-29 | — | — | CN | disclosed |