Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49741 | 0.88 | TSHR (0.52) | HDAC3HDAC11HDAC8HDAC6TSHR | |
| SCHEMBL2392625 | 0.88 | TSHR (0.52) | HDAC3HDAC11HDAC8HDAC6TSHR | |
| SCHEMBL5758 | 0.85 | TSHR (0.55) | TSHRHDAC1MEN1KMT2ANPC1 | |
| SCHEMBL6131645 | 0.83 | APP (0.48) | RAPGEF4HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL4629995 | 0.83 | APP (0.48) | RAPGEF4HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL3202679 | 0.83 | TSHR (0.52) | TSHRHDAC1MEN1KMT2ANPC1 | |
| SCHEMBL2957181 | 0.81 | KIF11 (0.57) | TSHRMEN1KMT2AHTTNPC1 | |
| SCHEMBL13321302 | 0.81 | KIF11 (0.57) | TSHRMEN1KMT2AHTTNPC1 | |
| SCHEMBL22432523 | 0.81 | TSHR (0.46) | HDAC3HDAC11HDAC8HDAC6TSHR | |
| SCHEMBL5396983 | 0.81 | TSHR (0.46) | HDAC3HDAC11HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102725350-B | Composition and light emitting element using the composition | SUMITOMO CHEMICAL CO | 2014-08-27 | — | — | CN | disclosed |
| CN-102725350-A | Composition and light emitting element using the composition | SUMITOMO CHEMICAL CO | 2012-10-10 | — | — | CN | disclosed |