Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629995 | 0.97 | APP (0.48) | APPKIF11RAPGEF4XDHSLC22A12 | |
| SCHEMBL1086767 | 0.85 | RAPGEF4 (0.54) | APPRAPGEF4 | |
| SCHEMBL28801068 | 0.83 | RAPGEF4 (0.44) | APPKIF11RAPGEF4MEN1KMT2A | |
| SCHEMBL10002565 | 0.82 | APP (0.55) | APPRAPGEF4MEN1KMT2A | |
| SCHEMBL6131646 | 0.81 | AKR1C3 (0.39) | APPKIF11RAPGEF4XDHSLC22A12 | |
| SCHEMBL4629998 | 0.80 | AKR1C3 (0.36) | APPKIF11XDHSLC22A12AKR1C3 | |
| SCHEMBL27650113 | 0.80 | MAPT (0.50) | APPKIF11XDHSLC22A12MEN1 | |
| SCHEMBL28468095 | 0.79 | ALDH1A1 (0.52) | APPMEN1KMT2A | |
| SCHEMBL4311216 | 0.77 | APP (0.49) | APPMEN1KMT2A | |
| SCHEMBL4823761 | 0.76 | HPGD (0.39) | MEN1KMT2ASERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956095-B2 | Process for producing aryl—aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-10-18 | — | — | US | disclosed |