SCHEMBL49741

SCHEMBL49741

CC(C)(C)c1ccc(Nc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPK1 P28482 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
XBP1 P17861 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
KIF11 P52732 1/20 0.47
HDAC3 O15379 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
EPHX2 P34913 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
DHODH Q02127 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2392625 1.00 TSHR (0.52) TSHRLMNATYRNPC1RAB9A
SCHEMBL22432523 0.92 TSHR (0.46) TSHRLMNATYRNPC1RAB9A
SCHEMBL2957181 0.92 KIF11 (0.57) TSHRLMNATYRNPC1RAB9A
SCHEMBL5396983 0.92 TSHR (0.46) TSHRLMNATYRNPC1RAB9A
SCHEMBL13321302 0.92 KIF11 (0.57) TSHRLMNATYRNPC1RAB9A
SCHEMBL12278117 0.90 TSHR (0.71) TSHRLMNATYRNPC1RAB9A
SCHEMBL502030 0.90 ALDH1A1 (0.62) TSHRLMNARAB9ASMN1; SMN2MAPK1
SCHEMBL24137667 0.88 TSHR (0.42) TSHRLMNATYRNPC1RAB9A
SCHEMBL20683954 0.88 TSHR (0.42) TSHRLMNATYRNPC1RAB9A
SCHEMBL5539876 0.88 DHODH (0.42) TSHRLMNATYRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1785 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622168-B2 Organic light emitting diode and organic light emitting device including thereof LG DISPLAY CO., LTD. (KR) 2026-05-05 US claimed
US-20260078239-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION NYCO (FR) 2026-03-19 US claimed
EP-4514928-B1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2026-01-28 EP claimed
CN-120025277-A Key bromine-containing intermediate for synthesizing TADF molecule and synthesis method thereof 南京理工大学 2025-05-23 CN claimed
WO-2025084975-A1 A BI-PHASIC ELECTROLYSIS CELL FOR CARBON DIOXIDE CAPTURE, ELECTROCATALYSTS FOR USE IN THE CELL, RELATED METHODS AND A PRODUCTION FACILITY USING THE ELECTROLYSIS CELL AND THE ELECTROCATALYSTS CarbGen AB (SE) 2025-04-24 WO claimed
US-20250110399-A1 PHOTOSENSITIVE COMPOSITION CONTAINING PFAS-FREE POLYCYCLOOLEFINIC TERPOLYMERS AND SEMICONDUCTOR DEVICE MADE THEREOF PROMERUS, LLC (US) 2025-04-03 US claimed
US-20250110403-A1 PHOTOSENSITIVE COMPOSITION CONTAINING PFAS-FREE POLYCYCLOOLEFINIC POLYMERS AND SEMICONDUCTOR DEVICE MADE THEREOF PROMERUS, LLC (US) 2025-04-03 US claimed
EP-4514928-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2025-03-05 EP claimed
CN-119192558-A Polyphenylene ether resin, composition, preparation method and application thereof 万华化学集团股份有限公司 2024-12-27 CN claimed
US-20240360295-A1 STABILIZER COMBINATION FOR PREVENTING DEGRADATION OF SYNTHETIC POLYMERS BASF SE (DE) 2024-10-31 US claimed
EP-0543778-A1 Compositions protected against oxydation and scorching, respectively polyetherpolyol and polyurethane CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
US-5167844-A Stabilized against thermal and oxidative degradation CIBA-GEIGY CORPORATION (US) 1992-12-01 US claimed
EP-0346283-B1 LUBRICANT COMPOSITION CIBA-GEIGY AG (CH) 1992-07-29 EP claimed
EP-0480875-A1 Lubricating composition CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
US-5091099-A Phosphite-free; containing aromatic amines and substituted phenols CIBA-GEIGY CORPORATION (US) 1992-02-25 US claimed
EP-0432089-A1 Lubricating oil compositions CIBA-GEIGY AG (CH) 1991-06-12 EP claimed
EP-0398215-A1 Lubricant compositions CIBA-GEIGY AG (CH) 1990-11-22 EP claimed
US-4963276-A MIXTURE OF AROMATIC AMINE AND ORGANOSULFUR COMPOUND CIBA-GEIGY CORPORATION (US) 1990-10-16 US claimed
EP-0346283-A2 Lubricant composition CIBA-GEIGY AG (CH) 1989-12-13 EP claimed
EP-0323403-A2 Lubricant composition CIBA-GEIGY AG (CH) 1989-07-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078239-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION GPX4, RAD50, POT1 TSHR 615/4885LMNA 1245/4885TYR 3360/4885
US-12622168-B2 Organic light emitting diode and organic light emitting device including thereof OCIAD1, OCIAD2, MAP1LC3C TSHR 3238/4885LMNA 700/4885TYR 691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.