Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274939 | 0.87 | LMNA (0.45) | LMNAMAPTHTT | |
| SCHEMBL15662405 | 0.79 | MEN1 (0.60) | HSD17B10LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL30922256 | 0.78 | FFAR1 (0.44) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5906474 | 0.76 | HTT (0.46) | HSD17B10MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6280404 | 0.76 | PKM (0.49) | MAPTALDH1A1 | |
| SCHEMBL2891612 | 0.75 | KLKB1 (0.39) | MAPTSMN1; SMN2KMT2AMEN1CYP1A2 | |
| SCHEMBL5906425 | 0.75 | LMNA (0.42) | HSD17B10LMNAMAPTPOLBTDP1 | |
| SCHEMBL5906347 | 0.74 | LMNA (0.48) | LMNAMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL5906284 | 0.74 | MEN1 (0.47) | HSD17B10MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5906268 | 0.74 | CYP19A1 (0.45) | MAPTL3MBTL1ALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425756-A | Adenosine receptor antagonist compounds and uses thereof | 日东制药株式会社 | 2023-07-14 | — | — | CN | disclosed |
| CN-114829363-A | Adenosine receptor antagonist compounds | 日东制药株式会社 | 2022-07-29 | — | — | CN | disclosed |