Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525426 | 0.81 | KDM4E (0.50) | PKMCYP19A1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL5906284 | 0.78 | MEN1 (0.47) | PKMMAPTALDH1A1HTR1AHTR2C | |
| SCHEMBL6274939 | 0.78 | LMNA (0.45) | MAPT | |
| SCHEMBL5906474 | 0.78 | HTT (0.46) | CYP19A1HDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL994055 | 0.77 | CYP19A1 (0.57) | PKMCYP19A1HDAC1HDAC6MAPT | |
| SCHEMBL5906425 | 0.77 | LMNA (0.42) | MAPTALDH1A1 | |
| SCHEMBL28801093 | 0.76 | HSD17B10 (0.49) | MAPTALDH1A1 | |
| SCHEMBL5906268 | 0.76 | CYP19A1 (0.45) | CYP19A1MAPTALDH1A1HTR1A | |
| SCHEMBL5906197 | 0.76 | CYP19A1 (0.51) | CYP19A1HDAC1HDAC6HTR1AADRA2C | |
| SCHEMBL2728791 | 0.75 | CYP19A1 (0.57) | PKMCYP19A1HDAC1HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606271-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080984-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | WO | disclosed |