Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844911 | 0.83 | MEN1 (0.46) | LMNAFKBP1APOLBPTGER4XIAP | |
| SCHEMBL28801373 | 0.79 | LMNA (0.41) | LMNAFKBP1APOLBPTGER4XIAP | |
| SCHEMBL4842372 | 0.74 | LMNA (0.48) | LMNAFKBP1APOLBALDH1A1MEN1 | |
| SCHEMBL926246 | 0.72 | EPHX2 (0.48) | LMNAFKBP1APOLBXIAPALDH1A1 | |
| SCHEMBL4844332 | 0.69 | MEN1 (0.40) | LMNAFKBP1AMEN1CYP3A4CYP2D6 | |
| SCHEMBL4832807 | 0.69 | MAPT (0.44) | LMNAFKBP1AMEN1CYP3A4CYP2D6 | |
| SCHEMBL4838603 | 0.68 | RAB9A (0.44) | LMNAFKBP1APOLBMEN1CYP3A4 | |
| SCHEMBL4842829 | 0.68 | SCN9A (0.48) | LMNAFKBP1APOLBMEN1CYP3A4 | |
| SCHEMBL4844942 | 0.67 | RORC (0.43) | PTGER4MEN1CYP3A4CYP2D6MAPT | |
| SCHEMBL27516582 | 0.67 | LMNA (0.40) | LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746214-A | Novel indoline compounds | FOURNIER LAB SA | 2012-10-24 | — | — | CN | disclosed |