Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC19A2 | O60779 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3642529 | 0.91 | ADORA2A (0.39) | TLR7TLR8ADORA3ADORA2AADORA2B | |
| SCHEMBL4802103 | 0.81 | DHFR (0.38) | GPR84DHFRTLR7TLR8ADORA3 | |
| SCHEMBL11002501 | 0.79 | MAPT (0.36) | GPR84TLR7TLR8ADORA3ADORA2A | |
| SCHEMBL26800975 | 0.78 | KDM4E (0.42) | DHFRTLR7TLR8KDM4ESLC19A2 | |
| SCHEMBL11001073 | 0.78 | MAPT (0.39) | GPR84TLR7ADORA3ADORA2AKCNH2 | |
| SCHEMBL28012718 | 0.75 | ADORA1 (0.33) | DHFRADORA1KDM4ESLC19A2USP2 | |
| SCHEMBL19714623 | 0.74 | HTR2C (0.48) | DHFRADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL83448 | 0.74 | KDM4E (0.54) | GPR84TLR7TLR8PI4KAPI4K2B | |
| SCHEMBL28477825 | 0.73 | DHFR (0.45) | DHFRTLR8KDM4ESLC19A2USP2 | |
| SCHEMBL15894462 | 0.72 | RAB9A (0.57) | GPR84TLR7TLR8KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | disclosed |