Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551053 | 0.84 | DHFR (0.45) | DHFRMEN1KMT2AKDM4EGAA | |
| SCHEMBL11002501 | 0.81 | MAPT (0.36) | MEN1KMT2AKDM4EGAAHSD17B10 | |
| Benzene SCHEMBL28801411 | 0.81 | GPR84 (0.41) | DHFRKDM4EUSP2TDP1TLR7 | |
| SCHEMBL4941629 | 0.80 | TDP1 (0.37) | DHFRMEN1KMT2AKDM4EGAA | |
| SCHEMBL11001073 | 0.79 | MAPT (0.39) | MEN1KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL3642529 | 0.78 | ADORA2A (0.39) | MEN1KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL83448 | 0.75 | KDM4E (0.54) | MEN1KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL27884409 | 0.74 | HRH3 (0.36) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL11577082 | 0.74 | GCGR (0.36) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL17967585 | 0.73 | RAB9A (0.57) | MEN1KMT2AKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805301-B | 2, 4-diaryl aminopyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2024-04-05 | — | — | CN | claimed |
| CN-116003331-A | 2, 4-diarylaminopyrimidine derivative and application thereof | 浙江工业大学 | 2023-04-25 | — | — | CN | claimed |
| CN-110218205-B | 2, 4-diarylaminopyrimidine derivatives containing pyridine structure and application thereof | 辽宁大学 | 2022-04-05 | — | — | CN | claimed |
| CN-111484484-B | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2021-11-23 | — | — | CN | claimed |
| CN-111484484-A | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2020-08-04 | — | — | CN | claimed |
| CN-114805301-B | 2, 4-diaryl aminopyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-114805301-B | 2, 4-diaryl aminopyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-114805301-B | 2, 4-diaryl aminopyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116003331-A | 2, 4-diarylaminopyrimidine derivative and application thereof | 浙江工业大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-116003331-A | 2, 4-diarylaminopyrimidine derivative and application thereof | 浙江工业大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114805301-A | 2, 4-diarylaminopyrimidine compounds and preparation method and application thereof | 沈阳药科大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805301-A | 2, 4-diarylaminopyrimidine compounds and preparation method and application thereof | 沈阳药科大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-111484484-B | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-111484484-B | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-111484484-B | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-111484484-A | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-111484484-A | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-111484484-A | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-108329232-A | Hydrazide derivative and its application | 浙江大学 | 2018-07-27 | — | — | CN | disclosed |
| WO-2008060866-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |