SCHEMBL2880144

SCHEMBL2880144

BrCCc1c(Br)c(Br)c(Br)c(Br)c1CCBr

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
PTPN1 P18031 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9512166 0.93 TDP1 (0.30) TDP1CA1CA2PTPN1CA4
SCHEMBL9861590 0.90
SCHEMBL9860827 0.89 TDP1 (0.32) TDP1CA1CA2PTPN1CA4
SCHEMBL10751050 0.80
SCHEMBL21869865 0.78 CA2 (0.34) CA1CA2CA4CA6
SCHEMBL10456443 0.78
SCHEMBL332145 0.72 CA1 (0.35) CA1CA2PTPN1CA4CA6
SCHEMBL11224021 0.69 CA1 (0.33) CA1CA2PTPN1CA4CA6
SCHEMBL180611 0.69 CA1 (0.33) CA1CA2PTPN1CA4CA6
SCHEMBL10831875 0.68 THRB (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010530439-A 2010-09-09 JP claimed
EP-2115059-A1 FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS CHEMTURA CORPORATION (US) 2009-11-11 EP claimed
WO-2008127753-A1 FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS CHEMTURA CORPORATION (US) 2008-10-23 WO claimed
EP-2115059-A1 FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS CHEMTURA CORPORATION (US) 2009-11-11 EP disclosed
WO-2008127753-A1 FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS CHEMTURA CORPORATION (US) 2008-10-23 WO disclosed
EP-0336361-B1 SULFUR-CONTAINING ACRYL OLIGOMER COMPOSITION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-04-10 EP disclosed
US-4990653-A Curable; plastic lenses; transparency, optical uniformity MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-02-05 US disclosed
EP-0336361-A1 Sulfur-containing acryl oligomer composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-10-11 EP disclosed