SCHEMBL9512166

SCHEMBL9512166

BrCCc1c(Br)c(Br)c(Br)c(Br)c1Br

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
PTPN1 P18031 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861590 0.97
SCHEMBL9860827 0.96 TDP1 (0.32) TDP1CA1CA2PTPN1CA4
SCHEMBL2880144 0.93 TDP1 (0.30) TDP1CA1CA2PTPN1CA4
SCHEMBL21869865 0.84 CA2 (0.34) CA1CA2CA4CA6
SCHEMBL332145 0.81 CA1 (0.35) CA1CA2PTPN1CA4CA6
SCHEMBL10751050 0.80
SCHEMBL10456443 0.78
Ethane SCHEMBL18094355 0.74 CA2 (0.33) CA1CA2PTPN1CA4CA6
SCHEMBL6855074 0.74 CA1 (0.32) CA1CA2PTPN1CA4CA6
SCHEMBL10831875 0.74 THRB (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0043906-B1 PROCESS FOR THE PREPARATION OF PENTA-BROMOSTYRENE POLYMERS AND THEIR USE Chemische Fabrik Kalk GmbH (DE) 1984-04-25 EP claimed
US-4394484-A Polypentabromostyrene, process for the production and use CHEMISCHE FABRIK KALK GMBH (DE) 1983-07-19 US claimed
US-4301058-A BROMINE COMPOUNDS WHICH MELT AT DIFFERENT TEMPERATURES CHEMISCHE FABRIK KALK GMBH (DE) 1981-11-17 US claimed
JP-5009227-A None JP disclosed
CN-105102410-A Preparation of bromine-containing aromatic compounds and their use as flame retardants BROMINE COMPOUNDS LTD 2015-11-25 CN disclosed
CN-102333816-A Styrene polymer composition ICL IP AMERICA INC 2012-01-25 CN disclosed
CN-1989188-B Novel flame-retardant polystyrenes BROMINE COMPOUNDS LTD 2010-05-12 CN disclosed
CN-1989188-A Novel flame-retardant polystyrenes BROMINE COMPOUNDS LTD (IL) 2007-06-27 CN disclosed
JP-H059227-A PREPARATION OF POLYPENTABROMOSTYRENE CHEM FAB KALK GMBH 1993-01-19 JP disclosed
US-4960962-A FORMING MONO-, DI-AND TRIBROMOSTYRENE WITHOUT USING A CATALYST ETHYL CORPORATION (US) 1990-10-02 US disclosed
US-4686311-A Dehydrohalogenation of haloethyl brominated benzenes ETHYL CORPORATION (US) 1987-08-11 US disclosed
US-4602111-A FLAME RETARDANT PPG INDUSTRIES, INC. (US) 1986-07-22 US disclosed
US-4394484-A Polypentabromostyrene, process for the production and use CHEMISCHE FABRIK KALK GMBH (DE) 1983-07-19 US disclosed
US-4394484-A Polypentabromostyrene, process for the production and use CHEMISCHE FABRIK KALK GMBH (DE) 1983-07-19 US disclosed
US-4301058-A BROMINE COMPOUNDS WHICH MELT AT DIFFERENT TEMPERATURES CHEMISCHE FABRIK KALK GMBH (DE) 1981-11-17 US disclosed