SCHEMBL2880153

SCHEMBL2880153

C#CNC(=O)C=CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
TSHR P16473 2/20 0.45
TP53 P04637 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
EGLN3 Q9H6Z9 1/20 0.45
ALDH1A1 P00352 5/20 0.43
GAA P10253 3/20 0.43
POLB P06746 1/20 0.41
LMNA P02545 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
LPAR2 Q9HBW0 2/20 0.38
LPAR3 Q9UBY5 1/20 0.38
HTT P42858 1/20 0.38
NPC1 O15118 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MAPT P10636 2/20 0.36
LPAR1 Q92633 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15048668 0.75 L3MBTL1 (0.55) L3MBTL1TSHRTP53EGLN1EGLN3
SCHEMBL1755617 0.75 L3MBTL1 (0.55) L3MBTL1TSHRTP53EGLN1EGLN3
SCHEMBL15048669 0.75 L3MBTL1 (0.55) L3MBTL1TSHRTP53EGLN1EGLN3
SCHEMBL25406284 0.73 GAA (0.46) L3MBTL1TSHRTP53EGLN1EGLN3
SCHEMBL10338437 0.69 TSHR (0.60) L3MBTL1TSHRTP53EGLN1EGLN3
SCHEMBL15087214 0.69 ALDH1A1 (0.52) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL13381419 0.69 ALDH1A1 (0.52) TSHRTP53EGLN1EGLN3ALDH1A1
Maleic Acid SCHEMBL613 0.67
Fumaric Acid SCHEMBL2046433 0.67 TSHR (1.00) TSHRTP53EGLN1EGLN3ALDH1A1
Maleic Acid SCHEMBL20487516 0.67 TSHR (1.00) TSHRTP53EGLN1EGLN3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778804-B1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2010-01-20 EP claimed
EP-0875541-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2003-09-10 EP claimed
EP-0875540-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2002-11-13 EP claimed
EP-0875541-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP claimed
EP-0875540-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP claimed
EP-1778804-B1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2010-01-20 EP disclosed
EP-1778804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS Arkema France (FR) 2007-05-02 EP disclosed
WO-2006010804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2006-02-02 WO disclosed
EP-0875541-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2003-09-10 EP disclosed
EP-0875540-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2002-11-13 EP disclosed
EP-0875541-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP disclosed
EP-0875540-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP disclosed