SCHEMBL15048668

SCHEMBL15048668

C#CCNC(=O)/C=C/C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
MAOB P27338 1/20 0.50
MAOA P21397 1/20 0.46
ALDH1A1 P00352 6/20 0.44
LMNA P02545 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
GAA P10253 2/20 0.43
KMT2A Q03164 1/20 0.42
TAAR1 Q96RJ0 3/20 0.42
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1755617 1.00 L3MBTL1 (0.55) L3MBTL1RAB9ASMN1; SMN2NPC1MAOB
SCHEMBL15048669 1.00 L3MBTL1 (0.55) L3MBTL1RAB9ASMN1; SMN2NPC1MAOB
SCHEMBL14619698 0.83 RAB9A (0.50) L3MBTL1RAB9ASMN1; SMN2NPC1MAOB
SCHEMBL14587454 0.79 HCAR2 (0.52) L3MBTL1RAB9ASMN1; SMN2NPC1MAOB
SCHEMBL14587438 0.78 RAB9A (0.46) L3MBTL1RAB9ASMN1; SMN2NPC1MAOB
SCHEMBL803250 0.76 ALDH1A1 (0.51) L3MBTL1ALDH1A1LMNACYP2D6CYP2C19
SCHEMBL15286318 0.75 RAB9A (0.47) L3MBTL1RAB9ASMN1; SMN2NPC1MAOB
SCHEMBL15286321 0.75 RAB9A (0.47) L3MBTL1RAB9ASMN1; SMN2NPC1MAOB
SCHEMBL1395639 0.75 ALDH1A1 (0.53) L3MBTL1ALDH1A1LMNACYP2D6CYP2C19
SCHEMBL2880153 0.75 L3MBTL1 (0.46) L3MBTL1SMN1; SMN2NPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118257004-A Method for screening molecular library from molecular library of DCL-ABPP 华南理工大学 2024-06-28 CN claimed
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2025-12-30 US disclosed
EP-4658314-A1 MAGNETIC HYDROGEL PARTICLES AND METHODS OF USE The Regents of the University of California (US) 2025-12-10 EP disclosed
CN-118267478-B Application of agent for silencing or inhibiting LPCAT1 gene in induction of iron death of tumor cells 中山大学 2025-05-16 CN disclosed
CN-119192236-B Serine hydrolase inhibitor and preparation method and application thereof 西北农林科技大学深圳研究院 2025-03-11 CN disclosed
CN-119192236-A Serine hydrolase inhibitor and preparation method and application thereof 西北农林科技大学深圳研究院 2024-12-27 CN disclosed
WO-2024163471-A1 MAGNETIC HYDROGEL PARTICLES AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-08 WO disclosed
CN-118384290-A Hybrid immunoglobulins containing non-peptide linkages 生物分子控股有限责任公司 2024-07-26 CN disclosed
CN-118267478-A Application of agent for silencing or inhibiting LPCAT1 gene in induction of iron death of tumor cells 中山大学 2024-07-02 CN disclosed
CN-118257004-A Method for screening molecular library from molecular library of DCL-ABPP 华南理工大学 2024-06-28 CN disclosed
CN-118257004-A Method for screening molecular library from molecular library of DCL-ABPP 华南理工大学 2024-06-28 CN disclosed
EP-4169944-A1 PROCESS FOR PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2023-04-26 EP disclosed
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-09-01 US disclosed
EP-4039281-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2022-08-10 EP disclosed
EP-3701971-B1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-07-06 EP disclosed
EP-2607361-A1 Thiirane and michael acceptor compounds and their medical use Ludwig-Maximilians-Universität München (DE) 2013-06-26 EP disclosed
EP-2607361-A1 Thiirane and michael acceptor compounds and their medical use Ludwig-Maximilians-Universität München (DE) 2013-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, FCGR2A, VSIG8 L3MBTL1 2238/4885RAB9A 3740/4885SMN1; SMN2 4483/4885
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage FCGR2A, FCGR3B, CD74 L3MBTL1 1181/4885RAB9A 3901/4885SMN1; SMN2 3580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.