Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052008 | 0.79 | ALDH1A1 (0.40) | MAPTHTTALDH1A1MAPK1KMT2A | |
| SCHEMBL28061957 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL9078790 | 0.78 | TSHR (0.44) | MAPTHTTALDH1A1MAPK1NPSR1 | |
| SCHEMBL16831434 | 0.76 | PTGER4 (0.58) | MAPTHCAR3HTTALDH1A1NPC1 | |
| SCHEMBL27622467 | 0.73 | ITGB1 (0.50) | MAPTHTTALDH1A1RAB9AMAPK1 | |
| SCHEMBL28226522 | 0.72 | ALDH1A1 (0.41) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL28315507 | 0.72 | PDK1 (0.45) | MAPTHTTALDH1A1NPC1RAB9A | |
| SCHEMBL7440236 | 0.71 | TSHR (0.48) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL2426533 | 0.71 | KDM4E (0.46) | MAPTHCAR3HTTALDH1A1KMT2A | |
| SCHEMBL6491502 | 0.71 | SMN1; SMN2 (0.45) | MAPTHTTALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762101-A | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2012-10-31 | — | — | CN | disclosed |