Threonine

Threonine

SCHEMBL28801593

CC(O)C(N)C(=O)O.Cc1cc(=O)oc2cc(N)ccc12

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.68
KDM4E B2RXH2 10/20 0.68
HPGD P15428 8/20 0.68
HSD17B10 Q99714 6/20 0.68
GLA P06280 5/20 0.68
GAA P10253 5/20 0.68
CA12 O43570 4/20 0.68
CA9 Q16790 4/20 0.68
CA1 P00915 3/20 0.68
CASP1 P29466 2/20 0.68
CASP7 P55210 2/20 0.68
ALDH2 P05091 1/20 0.50
AR P10275 1/20 0.50
LMNA P02545 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
AKR1B1 P15121 1/20 0.49
UGT1A1 P22309 1/20 0.49
MAOB P27338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL336393 0.91 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10GLA
Valine SCHEMBL6242121 0.91 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10GLA
Alanine SCHEMBL335764 0.90 ALDH1A1 (0.75) ALDH1A1KDM4EHPGDHSD17B10GLA
Alanine SCHEMBL27923846 0.90 ALDH1A1 (0.75) ALDH1A1KDM4EHPGDHSD17B10GLA
D-Alanine SCHEMBL4187196 0.90 ALDH1A1 (0.75) ALDH1A1KDM4EHPGDHSD17B10GLA
Isoleucine SCHEMBL7218421 0.87 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDHSD17B10GLA
Isoleucine SCHEMBL27913720 0.87 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDHSD17B10GLA
Isoleucine SCHEMBL4186315 0.87 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDHSD17B10GLA
Acetic Acid SCHEMBL3998167 0.84 ALDH1A1 (0.84) ALDH1A1KDM4EHPGDHSD17B10GLA
Leucine SCHEMBL19695473 0.83 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102994387-A High throughput screening method of aminopeptidase and high-yield strain thereof TIANJIN INST IND BIOTECHNOLOGY 2013-03-27 CN claimed
CN-102994387-A High throughput screening method of aminopeptidase and high-yield strain thereof TIANJIN INST IND BIOTECHNOLOGY 2013-03-27 CN disclosed