Valine

Valine

SCHEMBL336393

CC(C)[C@H](N)C(=O)O.Cc1cc(=O)oc2cc(N)ccc12

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.69
KDM4E B2RXH2 9/20 0.69
HPGD P15428 7/20 0.69
HSD17B10 Q99714 5/20 0.69
GLA P06280 5/20 0.69
GAA P10253 5/20 0.69
CA12 O43570 4/20 0.69
CA9 Q16790 4/20 0.69
CA1 P00915 3/20 0.69
CASP1 P29466 2/20 0.69
CASP7 P55210 2/20 0.69
ALDH2 P05091 1/20 0.51
AR P10275 1/20 0.51
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
AKR1B1 P15121 1/20 0.50
UGT1A1 P22309 1/20 0.50
MAOB P27338 1/20 0.50
KDR P35968 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL6242121 1.00 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10GLA
Threonine SCHEMBL28801593 0.91 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDHSD17B10GLA
Alanine SCHEMBL335764 0.91 ALDH1A1 (0.75) ALDH1A1KDM4EHPGDHSD17B10GLA
Alanine SCHEMBL27923846 0.91 ALDH1A1 (0.75) ALDH1A1KDM4EHPGDHSD17B10GLA
D-Alanine SCHEMBL4187196 0.91 ALDH1A1 (0.75) ALDH1A1KDM4EHPGDHSD17B10GLA
Isoleucine SCHEMBL27913720 0.88 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDHSD17B10GLA
Isoleucine SCHEMBL4186315 0.88 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDHSD17B10GLA
Isoleucine SCHEMBL7218421 0.88 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDHSD17B10GLA
D-Glutamate SCHEMBL27827072 0.86 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDHSD17B10GLA
Acetic Acid SCHEMBL3998167 0.85 ALDH1A1 (0.84) ALDH1A1KDM4EHPGDHSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101551333-B Composition for cell permeabilization comprising nog, hmp, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP 2012-11-28 CN claimed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP claimed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP claimed
CN-101551333-A Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2009-10-07 CN claimed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US claimed
WO-1995000660-A1 METHOD FOR ASSESSING MICROORGANISM VIABILITY CHEMUNEX (FR) 1995-01-05 WO claimed
EP-3115068-B1 WOUND DRESSING COMPOSITIONS COMPRISING CHITOSAN AND AN OXIDISED CELLULOSE SYSTAGENIX WOUND MAN LIMITED (GB) 2020-07-22 EP disclosed
CN-107130013-A A kind of engineering bacteriophage quick detection microorganism of aminopeptidase mark 海南大学 2017-09-05 CN disclosed
EP-3115068-A1 WOUND DRESSING COMPOSITIONS COMPRISING CHITOSAN AND AN OXIDISED CELLULOSE Systagenix Wound Management IP Co. BV. (NL) 2017-01-11 EP disclosed
EP-1539258-B1 WOUND DRESSING COMPOSITIONS COMPRISING CHITOSAN AND AN OXIDISED CELLULOSE SYSTAGENIX WOUND MAN IP CO BV (NL) 2016-10-26 EP disclosed
CN-101551333-B Composition for cell permeabilization comprising nog, hmp, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP 2012-11-28 CN disclosed
US-8097404-B2 Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORPORATION (US) 2012-01-17 US disclosed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP disclosed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US disclosed
EP-1539258-A2 WOUND DRESSING COMPOSITIONS COMPRISING CHITOSAN AND AN OXIDISED CELLULOSE Johnson & Johnson Medical Ltd. (GB) 2005-06-15 EP disclosed
WO-2004026200-A2 WOUND DRESSING COMPOSITIONS COMPRISING CHITOSAN AND AN OXIDISED CELLULOSE JOHNSON & JOHNSON MEDICAL LIMITED (GB) 2004-04-01 WO disclosed
WO-1995000660-A1 METHOD FOR ASSESSING MICROORGANISM VIABILITY CHEMUNEX (FR) 1995-01-05 WO disclosed
EP-0333560-B1 Process for quantitative determination of micro organismes CHEMUNEX (FR) 1994-04-27 EP disclosed
WO-1989008714-A1 QUALITITIVE OR QUANTITITIVE PROCESS FOR RESEARCHING MICROORGANISMS, INSTALLATION FOR APPLICATION OF SAID PROCESS CHEMUNEX (FR) 1989-09-21 WO disclosed
EP-0333560-A1 Process for quantitative determination of micro organismes CHEMUNEX (FR) 1989-09-20 EP disclosed