Isoleucine

Isoleucine

SCHEMBL4186315

CC[C@H](C)[C@H](N)C(=O)O.Cc1cc(=O)oc2cc(N)ccc12

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.63
HPGD P15428 7/20 0.63
KDM4E B2RXH2 7/20 0.63
HSD17B10 Q99714 5/20 0.63
GLA P06280 5/20 0.63
GAA P10253 4/20 0.63
CASP1 P29466 3/20 0.63
CASP7 P55210 3/20 0.63
CA12 O43570 3/20 0.63
CA9 Q16790 3/20 0.63
CA1 P00915 2/20 0.63
IGLV6-57 P01721 7/20 0.49
AR P10275 2/20 0.48
ALDH2 P05091 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
ATM Q13315 1/20 0.47
HIF1A Q16665 1/20 0.47
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoleucine SCHEMBL27913720 1.00 ALDH1A1 (0.63) ALDH1A1HPGDKDM4EHSD17B10GLA
Isoleucine SCHEMBL7218421 1.00 ALDH1A1 (0.63) ALDH1A1HPGDKDM4EHSD17B10GLA
Valine SCHEMBL336393 0.88 ALDH1A1 (0.69) ALDH1A1HPGDKDM4EHSD17B10GLA
Valine SCHEMBL6242121 0.88 ALDH1A1 (0.69) ALDH1A1HPGDKDM4EHSD17B10GLA
Threonine SCHEMBL28801593 0.87 ALDH1A1 (0.68) ALDH1A1HPGDKDM4EHSD17B10GLA
Alanine SCHEMBL27923846 0.86 ALDH1A1 (0.75) ALDH1A1HPGDKDM4EHSD17B10GLA
Alanine SCHEMBL335764 0.86 ALDH1A1 (0.75) ALDH1A1HPGDKDM4EHSD17B10GLA
D-Alanine SCHEMBL4187196 0.86 ALDH1A1 (0.75) ALDH1A1HPGDKDM4EHSD17B10GLA
Leucine SCHEMBL1776947 0.82 ALDH1A1 (0.64) ALDH1A1HPGDKDM4EHSD17B10GLA
Leucine SCHEMBL19695473 0.82 ALDH1A1 (0.64) ALDH1A1HPGDKDM4EHSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352083-B1 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS INC (US) 2005-10-26 EP claimed
EP-1352083-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BioControl Systems, Inc. (US) 2003-10-15 EP claimed
US-20020058298-A1 Compositions and methods for detecting target microorganisms in a sample BIOCONTROL SYSTEM, INC. (US) 2002-05-16 US claimed
WO-2002018625-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS, INC. (US) 2002-03-07 WO claimed
US-6022698-A Method and components for the detection of yeasts and/or molds in a sample IDEXX LABORATORIES, INCORPORATED (US) 2000-02-08 US claimed
EP-0946746-A1 METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1999-10-06 EP claimed
US-5854011-A Method and components for the detection of yeasts and/or molds in a sample IDEXX LABORATORIES INCORPORATED (US) 1998-12-29 US claimed
WO-1998027223-A1 METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE IDEXX LABORATORIES, INCORPORATED (US) 1998-06-25 WO claimed
US-7560246-B2 Compositions and methods for detecting target microorganisms in a sample BIOCONTROL SYSTEMS, INC. (US) 2009-07-14 US disclosed
EP-0870054-B1 METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS BIOCONTROL SYSTEMS INC (US) 2008-07-30 EP disclosed
EP-1352083-B1 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS INC (US) 2005-10-26 EP disclosed
EP-1352083-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BioControl Systems, Inc. (US) 2003-10-15 EP disclosed
US-6472167-B1 MEASURE VIABLE BACTERIA AS A FUNCTION OF THE ACTIVITIES OF BACTERIAL ENZYMES, PHOSPHATASES, GLUCOSIDASES, AND AMINOPEPTIDASES; PRESENCE DETECTED BY A FLUORESCENT SIGNAL BIOCONTROL SYSTEMS, INC. 2002-10-29 US disclosed
US-20020058298-A1 Compositions and methods for detecting target microorganisms in a sample BIOCONTROL SYSTEM, INC. (US) 2002-05-16 US disclosed
US-6387650-B1 INNOCULATING AND INCUBATING TEST SAMPLE ON GROWTH MEDIUM HAVING ENZYME SUBSTRATES FOR PHOSPHATASE, GLYCOSIDASE, AND PEPTIDASE, THEN DETECTING OR MEASURING SIGNAL PRODUCED BY THE HYDROLYSIS OF THE SUBSTRATES BIOCONTROL SYSTEMS, INC. 2002-05-14 US disclosed
WO-2002018625-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS, INC. (US) 2002-03-07 WO disclosed
US-5854011-A Method and components for the detection of yeasts and/or molds in a sample IDEXX LABORATORIES INCORPORATED (US) 1998-12-29 US disclosed