Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28155619 | 0.95 | KEAP1 (0.54) | KEAP1NFE2L2TSHRSMN1; SMN2TRPA1 | |
| SCHEMBL28246241 | 0.81 | KEAP1 (0.61) | KEAP1NFE2L2TSHRSMN1; SMN2TRPA1 | |
| SCHEMBL5446748 | 0.81 | KEAP1 (0.56) | KEAP1NFE2L2TSHRSMN1; SMN2TRPA1 | |
| SCHEMBL5494561 | 0.80 | TRPA1 (0.61) | KEAP1NFE2L2TSHRSMN1; SMN2TRPA1 | |
| SCHEMBL40704 | 0.80 | — | — | |
| O-Xylene SCHEMBL28004462 | 0.78 | TSHR (0.59) | KEAP1NFE2L2TSHRSMN1; SMN2KMT2A | |
| O-Xylene SCHEMBL3381232 | 0.78 | TSHR (0.59) | KEAP1TSHRSMN1; SMN2KMT2ALMNA | |
| SCHEMBL3991790 | 0.77 | TRPA1 (0.52) | KEAP1NFE2L2TSHRSMN1; SMN2TRPA1 | |
| Potassium Ion SCHEMBL338797 | 0.77 | KMT2A (0.44) | KEAP1NFE2L2TSHRSMN1; SMN2TRPA1 | |
| SCHEMBL10651982 | 0.77 | KMT2A (0.44) | KEAP1NFE2L2TSHRSMN1; SMN2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102993902-A | High-firmness epoxy paint | SHANGHAI ZHENHUA HEAVY INDUSTRY CHANGZHOU COATINGS CO LTD | 2013-03-27 | — | — | CN | disclosed |