Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290953 | 0.80 | LMNA (0.41) | — | |
| SCHEMBL28292346 | 0.80 | ITGB3 (0.34) | — | |
| SCHEMBL28290925 | 0.80 | ITGB3 (0.34) | ALDH1A1 | |
| SCHEMBL28292352 | 0.76 | TDP1 (0.43) | ALDH1A1 | |
| SCHEMBL28290928 | 0.73 | — | — | |
| SCHEMBL28290921 | 0.72 | PPARG (0.40) | — | |
| SCHEMBL28290929 | 0.71 | ITGB3 (0.38) | — | |
| SCHEMBL28292350 | 0.70 | TAAR1 (0.39) | — | |
| SCHEMBL27885864 | 0.70 | MIF (0.35) | — | |
| SCHEMBL28292337 | 0.69 | TAAR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-B | Be used for the treatment of indole amides derivative and the related compound thereof of neurodegenerative disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-05-25 | — | — | CN | disclosed |
| CN-102803252-A | Indole amide derivatives and related compounds for use in the treatment of neurodegenerative diseases | UNIV LEUVEN KATH | 2012-11-28 | — | — | CN | disclosed |