SCHEMBL28292352

SCHEMBL28292352

O=COCCC1=NOC(COc2ccccc2)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
GRM2 Q14416 1/20 0.37
ALDH1A1 P00352 5/20 0.37
MAPT P10636 4/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
ESR1 P03372 1/20 0.37
POLB P06746 1/20 0.37
MIF P14174 2/20 0.36
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
MAPK1 P28482 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HRH3 Q9Y5N1 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28292350 0.89 TAAR1 (0.39) TDP1MIFITGB3ITGA2B
SCHEMBL28292337 0.88 TAAR1 (0.35) TDP1MIFITGB3ITGA2B
SCHEMBL28292346 0.83 ITGB3 (0.34) LMNAITGB3ITGA2BMEN1KMT2A
SCHEMBL28290953 0.83 LMNA (0.41) LMNAITGB3ITGA2BHRH3DRD1
SCHEMBL28290928 0.82
SCHEMBL28290921 0.81 PPARG (0.40) ITGB3ITGA2BCYP3A4MEN1KMT2A
SCHEMBL28290929 0.77 ITGB3 (0.38) LMNAITGB3ITGA2BMEN1KMT2A
SCHEMBL28145165 0.77 TDP1 (0.51) TDP1GRM2ALDH1A1MAPTKDM4E
SCHEMBL28801691 0.76 ALDH1A1 (0.32) ALDH1A1
SCHEMBL27629013 0.76 TSHR (0.40) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106572659-B Harmful arthropod agent for preventing and eliminating containing amide compound 住友化学株式会社 2019-05-10 CN disclosed