Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707161 | 0.81 | LMNA (0.43) | LMNAMAPTIL4I1MAPK1KMT2A | |
| SCHEMBL1706806 | 0.80 | IL4I1 (0.42) | LMNAMAPTIL4I1MAPK1KMT2A | |
| SCHEMBL27899558 | 0.79 | IL4I1 (0.36) | LMNAMAPTIL4I1MAPK1KMT2A | |
| SCHEMBL1706233 | 0.78 | LOXL2 (0.44) | LMNAMAPTIL4I1MAPK1KMT2A | |
| SCHEMBL27542428 | 0.75 | SMN1; SMN2 (0.44) | KMT2AMEN1POLBHTTL3MBTL1 | |
| SCHEMBL27899551 | 0.74 | IL4I1 (0.38) | LMNAMAPTIL4I1MAPK1KMT2A | |
| SCHEMBL4962122 | 0.74 | MAOB (0.51) | LMNAIL4I1MAPK1KMT2AMEN1 | |
| SCHEMBL3335985 | 0.73 | LMNA (0.59) | LMNAIL4I1MAPK1KMT2AMEN1 | |
| SCHEMBL1706746 | 0.72 | LMNA (0.40) | LMNAMAPTIL4I1MAPK1KMT2A | |
| SCHEMBL27899559 | 0.72 | LMNA (0.38) | LMNAMAPTIL4I1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803237-A | Oxazole and thiazole derivatives as alx receptor agonists | ACTELION PHARMACEUTICALS LTD | 2012-11-28 | — | — | CN | disclosed |