Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459276 | 0.83 | NPSR1 (0.69) | NPSR1LMNAHTTL3MBTL1DRD2 | |
| SCHEMBL11208493 | 0.79 | NPSR1 (0.66) | NPSR1LMNAHTTL3MBTL1DRD2 | |
| SCHEMBL3233569 | 0.79 | NPSR1 (0.66) | NPSR1LMNAHTTL3MBTL1DRD2 | |
| SCHEMBL9286065 | 0.79 | LMNA (0.65) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| Hydrochloric Acid SCHEMBL3233556 | 0.78 | NPSR1 (0.64) | NPSR1LMNAHTTL3MBTL1DRD2 | |
| SCHEMBL29448052 | 0.78 | NPSR1 (0.64) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL6904284 | 0.78 | LMNA (0.64) | NPSR1LMNAHTTL3MBTL1DRD2 | |
| SCHEMBL15630925 | 0.78 | LMNA (0.64) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL9172913 | 0.78 | NPSR1 (0.64) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL13253339 | 0.72 | NPSR1 (0.57) | NPSR1LMNAHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086834-B | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2015-05-27 | — | — | CN | claimed |
| CN-103086834-A | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2013-05-08 | — | — | CN | claimed |
| CN-103086834-B | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2015-05-27 | — | — | CN | disclosed |
| CN-103086834-A | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2013-05-08 | — | — | CN | disclosed |