Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448052 | 0.81 | NPSR1 (0.64) | LMNANPSR1HTTL3MBTL1PRNP | |
| SCHEMBL15630925 | 0.81 | LMNA (0.64) | LMNANPSR1HTTL3MBTL1PRNP | |
| SCHEMBL9172913 | 0.81 | NPSR1 (0.64) | LMNANPSR1HTTL3MBTL1PRNP | |
| SCHEMBL9286065 | 0.78 | LMNA (0.65) | LMNANPSR1HTTL3MBTL1PRNP | |
| SCHEMBL28802227 | 0.78 | NPSR1 (1.00) | LMNANPSR1HTTL3MBTL1PRNP | |
| SCHEMBL13253339 | 0.75 | NPSR1 (0.57) | LMNANPSR1HTTL3MBTL1PRNP | |
| SCHEMBL4463201 | 0.74 | NPSR1 (0.50) | LMNANPSR1HTTL3MBTL1KDM4E | |
| SCHEMBL9171286 | 0.71 | NPSR1 (0.47) | LMNANPSR1HTTL3MBTL1PRNP | |
| SCHEMBL9164056 | 0.71 | NPSR1 (0.47) | LMNANPSR1HTTL3MBTL1HTR2A | |
| SCHEMBL11931712 | 0.70 | LMNA (0.54) | LMNANPSR1HTTL3MBTL1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013641-B1 | Acylation agent | HALDOR TOPSOE AS (DK) | 2004-11-24 | — | — | EP | disclosed |
| EP-1013641-A2 | Acylation agent | Haldor Topsoe A/S (DK) | 2000-06-28 | — | — | EP | disclosed |