Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802227 | 0.83 | NPSR1 (1.00) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL3233569 | 0.68 | NPSR1 (0.66) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL11208493 | 0.68 | NPSR1 (0.66) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL9286065 | 0.67 | LMNA (0.65) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3233556 | 0.67 | NPSR1 (0.64) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL6904284 | 0.67 | LMNA (0.64) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL15630925 | 0.67 | LMNA (0.64) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL29448052 | 0.67 | NPSR1 (0.64) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL9172913 | 0.67 | NPSR1 (0.64) | NPSR1HTTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL31288703 | 0.66 | SIGMAR1 (0.78) | NPSR1SIGMAR1DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129549-A1 | Stable lamotrigine pharmaceutical compositions and processes for their preparation | RANBAXY LABORATORIES LIMITED (IN) | 2007-06-07 | — | — | US | claimed |
| EP-1608371-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES, LTD. (IN) | 2005-12-28 | — | — | EP | claimed |
| WO-2004082685-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-30 | — | — | WO | claimed |
| EP-0711756-B1 | Process for the production of benzyl-piperidylmethyl-indanone | BAYER AG (DE) | 1998-07-22 | — | — | EP | claimed |
| US-5606064-A | Process for the preparation of benzyl-piperidylmethyl-indanones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | claimed |
| JP-8225527-A | — | — | None | — | — | JP | disclosed |
| US-20070129549-A1 | Stable lamotrigine pharmaceutical compositions and processes for their preparation | RANBAXY LABORATORIES LIMITED (IN) | 2007-06-07 | — | — | US | disclosed |
| US-20070129549-A1 | Stable lamotrigine pharmaceutical compositions and processes for their preparation | RANBAXY LABORATORIES LIMITED (IN) | 2007-06-07 | — | — | US | disclosed |
| EP-1608371-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES, LTD. (IN) | 2005-12-28 | — | — | EP | disclosed |
| EP-1608371-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES, LTD. (IN) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004099142-A1 | HYDROBROMIDE SALT OF BENZYL-PIPERIDYLMETHYL-INDANONE AND ITS POLYMORPHS | RANBAXY LABORATORIES LIMITED (IN) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004082685-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-30 | — | — | WO | disclosed |
| EP-0711756-B1 | Process for the production of benzyl-piperidylmethyl-indanone | BAYER AG (DE) | 1998-07-22 | — | — | EP | disclosed |
| US-5606064-A | Process for the preparation of benzyl-piperidylmethyl-indanones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5606064-A | Process for the preparation of benzyl-piperidylmethyl-indanones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5606064-A | Process for the preparation of benzyl-piperidylmethyl-indanones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| JP-H08225527-A | PREPARATION OF BENZYL-PIPERIDYLMETHYL-INDANONES | BAYER AG | 1996-09-03 | — | — | JP | disclosed |
| EP-0711756-A1 | Process for the production of benzyl-piperidylmethyl-indanone | BAYER AG (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0711756-A1 | Process for the production of benzyl-piperidylmethyl-indanone | BAYER AG (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0711756-A1 | Process for the production of benzyl-piperidylmethyl-indanone | BAYER AG (DE) | 1996-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129549-A1 | Stable lamotrigine pharmaceutical compositions and processes for their preparation | KCNJ1, KCNJ8, KCNJ2 | NPSR1 2510/4885HTT 1065/4885LMNA 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.