SCHEMBL288024

SCHEMBL288024

N[C@H](Cc1ccncc1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.68
PTGS1 P23219 3/20 0.68
PKM P14618 2/20 0.68
ALPI P09923 1/20 0.68
XIAP P98170 1/20 0.68
HSD17B10 Q99714 2/20 0.66
ALOX15 P16050 3/20 0.53
HIF1A Q16665 3/20 0.53
KDM4E B2RXH2 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
USP2 O75604 1/20 0.53
EGFR P00533 1/20 0.53
LCK P06239 1/20 0.53
FYN P06241 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
HTR2A P28223 1/20 0.53
PTGS2 P35354 1/20 0.53
RECQL P46063 1/20 0.53
TPH1 P17752 1/20 0.53
GRB2 P62993 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122532 1.00 SLC7A5 (0.68) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL122533 1.00 SLC7A5 (0.68) SLC7A5PTGS1PKMALPIXIAP
Hydrochloric Acid SCHEMBL29401033 0.98 SLC7A5 (0.66) SLC7A5PTGS1PKMALPIXIAP
Hydrochloric Acid SCHEMBL5966992 0.98 SLC7A5 (0.66) SLC7A5PTGS1PKMALPIXIAP
Hydrochloric Acid SCHEMBL7327198 0.98 SLC7A5 (0.66) SLC7A5PTGS1PKMALPIXIAP
Hydrochloric Acid SCHEMBL5966996 0.98 SLC7A5 (0.66) SLC7A5PTGS1PKMALPIXIAP
Hydrochloric Acid SCHEMBL7327202 0.98 SLC7A5 (0.66) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL4062635 0.93 SLC7A5 (0.61) SLC7A5PTGS1PKMALPIXIAP
Trifluoroacetic Acid SCHEMBL3341612 0.91 GRB2 (0.62) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL31398347 0.89 SLC7A5 (0.61) SLC7A5PTGS1PKMALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100520-A1 PEPTIDE, PEPTIDE COMPLEX, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR CELL CULTURE, AND COMPOSITION FOR MEDICAL USE, DIAGNOSTIC USE, OR RESEARCH USE ペプチドリーム株式会社 2025-05-15 WO claimed
WO-2025079064-A1 INTERLEUKIN-17 PEPTIDOMIMETIC INHIBITORS PEPTICOM LTD. (IL) 2025-04-17 WO claimed
WO-2024206577-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-10-03 WO claimed
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US disclosed
EP-4673162-A1 PATHOGEN-SPECIFIC PEPTIDE TO BLOCK VIRULENCE-RELATED SIGNALING IN CANDIDA ALBICANS I3S - Instituto de Investigação e Inovação em Saúde, Associação (PT) 2026-01-07 EP disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
WO-2025217074-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2025-10-16 WO disclosed
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-10-09 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 EP disclosed
WO-2025100520-A1 PEPTIDE, PEPTIDE COMPLEX, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR CELL CULTURE, AND COMPOSITION FOR MEDICAL USE, DIAGNOSTIC USE, OR RESEARCH USE ペプチドリーム株式会社 2025-05-15 WO disclosed
EP-1377540-B1 INHIBITORS OF INTEGRIN ALPHA-V-BETA-6 MERCK PATENT GMBH (DE) 2008-12-03 EP disclosed
EP-1963362-A1 METASTIN DERIVATIVES AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2008-09-03 EP disclosed
WO-2008022444-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2008-02-28 WO disclosed
WO-2007072997-A1 METASTIN DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-06-28 WO disclosed
CN-1582271-A Inhibitors of integrin alpha v beta 6 MERCK PATENT GMBH (DE) 2005-02-16 CN disclosed
US-20040092454-A1 Inhibitors of integrin alphavbeta6 MERCK PATENT GMBH (DE) 2004-05-13 US disclosed
EP-1377540-A1 INHIBITORS OF INTEGRIN AvB6 MERCK PATENT GmbH (DE) 2004-01-07 EP disclosed
WO-2002074730-A1 INHIBITORS OF INTEGRIN αvβ¿6? MERCK PATENT GMBH (DE) 2002-09-26 WO disclosed
US-4504414-A Synthetic pyridyl-alanyl decapeptides having antiovulatory activity BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1985-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH SLC7A5 3871/4885PTGS1 962/4885PKM 4481/4885
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF KISS1R, GNRHR, PROKR1 SLC7A5 2164/4885PTGS1 3753/4885PKM 1213/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 SLC7A5 3352/4885PTGS1 842/4885PKM 4790/4885
US-20040092454-A1 Inhibitors of integrin alphavbeta6 ITGB6, ITGB1, ITGA1 SLC7A5 3449/4885PTGS1 2507/4885PKM 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.