Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084544 | 0.77 | LMNA (0.71) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1514657 | 0.74 | LMNA (0.67) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17935541 | 0.73 | LMNA (0.60) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17935512 | 0.72 | LMNA (0.79) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17925445 | 0.71 | LMNA (0.53) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17935540 | 0.71 | LMNA (0.57) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17925446 | 0.71 | LMNA (0.54) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28803056 | 0.70 | — | — | |
| SCHEMBL17925437 | 0.70 | KMT2A (0.63) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18236206 | 0.70 | RAB9A (0.74) | LMNATP53MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805334-B | QC and GSK-3 beta multi-targeting inhibitor and preparation method and application thereof | 深圳大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-114805334-A | QC and GSK-3 beta multi-target inhibitor and preparation method and application thereof | 深圳大学 | 2022-07-29 | — | — | CN | disclosed |