Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHAT | P28329 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138776 | 0.80 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL819646 | 0.79 | KDM4E (0.68) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL36974 | 0.79 | KDM4E (0.68) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL6027912 | 0.76 | KDM4E (0.54) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL27922293 | 0.76 | HDAC1 (0.45) | HDAC8HDAC6ALDH1A1LMNACA4 | |
| SCHEMBL3826539 | 0.75 | KDM4E (0.55) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL31602276 | 0.75 | KDM4E (0.57) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL553714 | 0.75 | KDM4E (0.57) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL553715 | 0.75 | KDM4E (0.57) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 | |
| SCHEMBL563352 | 0.75 | KDM4E (0.57) | MTNR1AMTNR1BKDM4EHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087105-B | Chiral phosphine ligand and comprise the metal catalyst of this part and their application | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-103087105-A | Chiral phosphine ligand and metal catalyst comprising same and application of chiral phosphine ligand and metal catalyst | SHANGHAI INST ORGANIC CHEM | 2013-05-08 | — | — | CN | disclosed |