Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626895 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR | |
| Hydrochloric Acid SCHEMBL27645555 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR | |
| Bromide SCHEMBL27692435 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR | |
| SCHEMBL29852444 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR | |
| SCHEMBL235125 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR | |
| SCHEMBL28900064 | 0.77 | TBXAS1 (0.47) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR | |
| SCHEMBL29963731 | 0.77 | TBXAS1 (0.47) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR | |
| SCHEMBL27787769 | 0.77 | SLC6A2 (0.52) | SMN1; SMN2LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL27558033 | 0.77 | CYP2C19 (0.47) | LMNAPOLBALDH1A1CYP2C19 | |
| SCHEMBL29931638 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAL3MBTL1TBXAS1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102892759-A | Nitrogen-containing heterocyclic compound having kynurenine production inhibitory action | KYOWA HAKKO KIRIN CO LTD | 2013-01-23 | — | — | CN | disclosed |