SCHEMBL235125

SCHEMBL235125

CCC(C(=O)O)c1cccnc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 3/20 0.50
GAA P10253 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
THRB P10828 1/20 0.50
HTT P42858 2/20 0.48
CFTR P13569 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
GOPC Q9HD26 1/20 0.47
KDM4E B2RXH2 2/20 0.47
TBXAS1 P24557 2/20 0.47
PDE4D Q08499 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
GRM8 O00222 1/20 0.45
GRM4 Q14833 1/20 0.45
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29852444 1.00 SMN1; SMN2 (0.50) SMN1; SMN2LMNAGAAL3MBTL1THRB
SCHEMBL744044 0.87 TBXAS1 (0.48) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL29931638 0.85 SMN1; SMN2 (0.49) SMN1; SMN2LMNAGAAL3MBTL1THRB
SCHEMBL2436131 0.85 SMN1; SMN2 (0.49) SMN1; SMN2LMNAGAAL3MBTL1THRB
SCHEMBL25287082 0.84 SMN1; SMN2 (0.50) SMN1; SMN2LMNAGAAL3MBTL1HTT
SCHEMBL31038319 0.84 SMN1; SMN2 (0.50) SMN1; SMN2LMNAGAAL3MBTL1HTT
Pyridine SCHEMBL8587529 0.84 LMNA (0.60) SMN1; SMN2LMNAGAATHRBHTT
SCHEMBL8461393 0.84 TBXAS1 (0.49) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL4779810 0.83 SMN1; SMN2 (0.49) SMN1; SMN2LMNAGAAL3MBTL1HTT
SCHEMBL4775271 0.83 SMN1; SMN2 (0.49) SMN1; SMN2LMNAGAAL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4314945-B1 ELECTROCHROMIC ELEMENT, ELECTROCHROMIC DISPLAY DEVICE, ELECTROCHROMIC LIGHT-CONTROLLING DEVICE, AND ELECTROLYTE COMPOSITION RICOH CO LTD (JP) 2025-12-17 EP claimed
WO-2011109441-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF MYREXIS, INC. (US) 2011-09-09 WO claimed
US-12522618-B2 Copper complexes for treatment of neurodegenerative disorders ALS THERAPY DEVELOPMENT INSTITUTE (US) 2026-01-13 US disclosed
US-20240368195-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS ALS THERAPY DEVELOPMENT INST (US) 2024-11-07 US disclosed
US-20240352073-A1 BICYCLIC PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR JANSSEN BIOTECH INC (US) 2024-10-24 US disclosed
US-12012422-B2 Copper complexes for treatment of neurodegenerative disorders ALS THERAPY DEVELOPMENT INSTITUTE (US) 2024-06-18 US disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed
EP-4204399-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS ALS Therapy Development Institute (US) 2023-07-05 EP disclosed
CN-116234800-A Copper complexes for the treatment of neurodegenerative disorders ALS治疗发展学会 2023-06-06 CN disclosed
US-20230054997-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS ALS THERAPY DEVELOPMENT INSTITUTE, 2023-02-23 US disclosed
US-20230054997-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS ALS THERAPY DEVELOPMENT INSTITUTE, 2023-02-23 US disclosed
US-4950674-A Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment A. H. ROBINS COMPANY, INCORPORATED (US) 1990-08-21 US disclosed
US-4632925-A INSULIN LOWERING ACTIVITY HOFFMANN-LA ROCHE INC. (US) 1986-12-30 US disclosed
EP-0068880-B1 PHOTOGRAPHIC ELEMENTS CAPABLE OF PROVIDING OXOINDOLIZINE AND OXOINDOLIZINIUM DYE COMPOUNDS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-08-07 EP disclosed
EP-0068876-B1 OXOINDOLIZINE AND OXOINDOLIZINIUM DYES AND PROCESSES FOR THEIR PREPARATION EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-03 EP disclosed
EP-0088128-A4 ANTIINFLAMMATORY AND ANALGETIC 4-PYRIDYLPYRIDAZIN(2H)-3-ONES. DIAMOND SHAMROCK CORP (US) 1984-04-06 EP disclosed
US-4433152-A ANTIINFLAMMATORY AGENT, ANTIALLERGEN OR ANTICOAGULANT NIPPON CHEMIPHAR CO., LTD. (JP) 1984-02-21 US disclosed
EP-0088128-A1 ANTIINFLAMMATORY AND ANALGETIC 4-PYRIDYLPYRIDAZIN(2H)-3-ONES DIAMOND SHAMROCK CORPORATION (US) 1983-09-14 EP disclosed
WO-1983000863-A1 ANTIINFLAMMATORY AND ANALGETIC 4-PYRIDYLPYRIDAZIN(2H)-3-ONES DIAMOND SHAMROCK CORP (US) 1983-03-17 WO disclosed
EP-0068876-A1 Oxoindolizine and oxoindolizinium dyes and processes for their preparation EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12012422-B2 Copper complexes for treatment of neurodegenerative disorders SOD1, SMN1; SMN2, CLN6 SMN1; SMN2 2/4885LMNA 1550/4885GAA 50/4885
US-20230054997-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS SOD1, SMN1; SMN2, CLN6 SMN1; SMN2 2/4885LMNA 1550/4885GAA 50/4885
US-20240352073-A1 BICYCLIC PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR IL23R, IL1RN, IL17A SMN1; SMN2 4392/4885LMNA 4245/4885GAA 4039/4885
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP SMN1; SMN2 2485/4885LMNA 3240/4885GAA 1341/4885
US-20240368195-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS SOD1, SMN1; SMN2, CLN6 SMN1; SMN2 2/4885LMNA 1550/4885GAA 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.