Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.38 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882785 | 0.87 | PRKAA2 (0.42) | FASNPRKAA2PIK3CAMLLT1MCHR1 | |
| SCHEMBL2880370 | 0.85 | MAOA (0.40) | FASNMAOAMAOBPRKAA2PIK3CA | |
| SCHEMBL2885155 | 0.84 | MCHR1 (0.41) | FASNMAOAMAOBPRKAA2PIK3CA | |
| SCHEMBL2883117 | 0.74 | MCHR1 (0.45) | FASNPRKAA2PIK3CAMCHR1KCNH2 | |
| SCHEMBL2883113 | 0.74 | MCHR1 (0.45) | FASNPRKAA2PIK3CAMCHR1KCNH2 | |
| SCHEMBL1001840 | 0.68 | MCHR1 (0.45) | PRKAA2EGLN1MCHR1KCNH2PRKAB2 | |
| SCHEMBL1001328 | 0.67 | DRD2 (0.36) | FASNPRKAA2PIK3CAMLLT1MLLT3 | |
| SCHEMBL2878240 | 0.66 | MCHR1 (0.41) | PRKAA2PIK3CAMCHR1KCNH2ACKR3 | |
| SCHEMBL12975715 | 0.66 | PRKAA2 (0.45) | PRKAA2MCHR1KCNH2ACKR3PRKAB2 | |
| SCHEMBL2880435 | 0.65 | PRKAA2 (0.44) | PRKAA2PIK3CAMCHR1PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MSD K.K. (JP) | 2010-12-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MC1R, MCHR1, MCHR2 | FASN 3762/4885MAOA 73/4885MAOB 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.