Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804126 | 1.00 | L3MBTL1 (0.57) | L3MBTL1PARP1AOC3TRPM8POLB | |
| SCHEMBL528282 | 0.83 | KMT2A (0.43) | L3MBTL1PARP1TDP1KMT2AALDH1A1 | |
| SCHEMBL12327035 | 0.83 | ALOX5 (0.61) | L3MBTL1TDP1 | |
| SCHEMBL29201240 | 0.81 | L3MBTL1 (0.48) | L3MBTL1AOC3POLBCES2CES1 | |
| SCHEMBL27298887 | 0.81 | L3MBTL1 (0.51) | L3MBTL1AOC3POLBMTNR1AMTNR1B | |
| SCHEMBL7188262 | 0.80 | L3MBTL1 (0.47) | L3MBTL1AOC3TRPM8POLBCES2 | |
| SCHEMBL7192135 | 0.80 | L3MBTL1 (0.47) | L3MBTL1AOC3POLBCES2CES1 | |
| SCHEMBL25226434 | 0.80 | L3MBTL1 (0.65) | L3MBTL1PARP1AOC3TRPM8POLB | |
| SCHEMBL3424145 | 0.80 | PARP1 (0.46) | PARP1AOC3TRPM8TDP1ALDH1A1 | |
| SCHEMBL3715003 | 0.80 | ADRB1 (0.50) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114804989-B | Purification method and racemization recycling of rivastigmine key chiral intermediate | 华中科技大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-114804989-A | Purification method and racemization recycling of rivastigmine key chiral intermediate | 华中科技大学 | 2022-07-29 | — | — | CN | disclosed |