SCHEMBL28804255

SCHEMBL28804255

CC(=CNC(=O)Nc1ccccc1O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.51
MAPT P10636 5/20 0.51
KMT2A Q03164 4/20 0.51
KDM4E B2RXH2 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
MEN1 O00255 3/20 0.47
LMNA P02545 3/20 0.47
HTT P42858 2/20 0.47
HPGD P15428 2/20 0.46
MMP1 P03956 2/20 0.45
MMP2 P08253 2/20 0.45
MMP9 P14780 2/20 0.45
TP53 P04637 1/20 0.44
GRIK1 P39086 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
MAPK1 P28482 1/20 0.43
NFKB2 Q00653 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28804384 0.83 HDAC1 (0.63) KDM4E
SCHEMBL28804294 0.81 GAA (0.54) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL5705928 0.76 SMN1; SMN2 (0.43) GAAMAPTKMT2AKDM4ETDP1
SCHEMBL7748013 0.76 NPC1 (0.54) GAAMAPTKMT2AKDM4ETDP1
SCHEMBL7097491 0.76 GAA (0.46) GAAMAPTKMT2AKDM4ETDP1
SCHEMBL7097494 0.76 GAA (0.46) GAAMAPTKMT2AKDM4ETDP1
SCHEMBL9400389 0.75 NPC1 (0.66) GAAMAPTKMT2AKDM4ETDP1
SCHEMBL28804276 0.74 MAOA (0.53) GAAMAPTKMT2AKDM4ENPC1
SCHEMBL7096383 0.73 MARS1 (0.47) GAAMAPTKMT2AKDM4ETDP1
SCHEMBL7096385 0.73 MARS1 (0.47) GAAMAPTKMT2AKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791361-B Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate 富士胶片株式会社 2022-06-03 CN disclosed