Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400389 | 0.83 | NPC1 (0.66) | NPC1RAB9AGAALMNAHTT | |
| SCHEMBL27599875 | 0.79 | CYP1A2 (0.59) | NPC1RAB9AGAALMNAHTT | |
| SCHEMBL27489385 | 0.79 | NPC1 (0.60) | NPC1RAB9AGAATP53KMT2A | |
| SCHEMBL20758958 | 0.77 | KDM4E (0.63) | NPC1RAB9AGAAKMT2AMAPT | |
| SCHEMBL28804255 | 0.76 | GAA (0.51) | NPC1RAB9AGAALMNAHTT | |
| SCHEMBL7094650 | 0.76 | ALDH1A1 (0.76) | NPC1RAB9AGAALMNAHTT | |
| SCHEMBL8641397 | 0.76 | MMP1 (0.61) | NPC1RAB9AGAALMNAHTT | |
| SCHEMBL9038777 | 0.76 | NPC1 (0.58) | NPC1RAB9AGAALMNAHTT | |
| SCHEMBL27582499 | 0.75 | ALDH1A1 (0.62) | NPC1RAB9AGAALMNAHTT | |
| SCHEMBL29473469 | 0.74 | NPC1 (0.63) | NPC1RAB9AGAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113006-A1 | Process for the synthesis of 2,5-dicarbonamidophenolic couplers and benzoxazole derivatives as intermediates | EASTMAN KODAK COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6201125-B1 | REDUCING A 2-ALKYL-6-NITRO-BENZOXAZOLE TO FORM A 2-ALKYL-6-AMINO-BENZOXAZOLE IN WHICH THE 2-ALKYL GROUP IS UNBRANCHED AT THE ALPHA CARBON; COUPLERS | EASTMAN KODAK COMPANY | 2001-03-13 | — | — | US | disclosed |