SCHEMBL28804378

SCHEMBL28804378

CCc1noc(CC)c1C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
LMNA P02545 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
HTT P42858 2/20 0.43
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL859684 0.84 TSHR (0.44) ALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL9428201 0.82 NPSR1 (0.42) ALDH1A1LMNAL3MBTL1HTT
SCHEMBL28567613 0.80 ALDH1A1 (0.37) ALDH1A1LMNAL3MBTL1HTTRAB9A
SCHEMBL10981633 0.79 NPSR1 (0.39) ALDH1A1APOBEC3AAPOBEC3GNPC1RAB9A
SCHEMBL4336590 0.78 LMNA (0.44) ALDH1A1LMNAL3MBTL1HTTRAB9A
SCHEMBL10801789 0.78 NPSR1 (0.41) ALDH1A1LMNAHTTAPOBEC3AAPOBEC3G
SCHEMBL9428901 0.78 LMNA (0.57) ALDH1A1LMNAL3MBTL1HTTNPC1
SCHEMBL18605355 0.77 LMNA (0.43) ALDH1A1LMNAL3MBTL1HTTRAB9A
SCHEMBL4348580 0.76 LMNA (0.42) ALDH1A1LMNAL3MBTL1HTTRAB9A
SCHEMBL18605168 0.75 ALDH1A1 (0.42) ALDH1A1LMNAL3MBTL1HTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894397-A Synthesis method of 3-oxo-2-propionyl methyl valerate 北京岳达生物科技有限公司 2023-04-04 CN disclosed
CN-114716389-A Synthetic method of 3, 5-diethylisoxazole-4-carboxylic acid 北京岳达生物科技有限公司 2022-07-08 CN disclosed